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Stacey M Bagby Selected Research

RX-5902

11/2020RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer.
11/2019First-in-Class Phosphorylated-p68 Inhibitor RX-5902 Inhibits β-Catenin Signaling and Demonstrates Antitumor Activity in Triple-Negative Breast Cancer.

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Stacey M Bagby Research Topics

Disease

24Neoplasms (Cancer)
01/2022 - 01/2014
7Melanoma (Melanoma, Malignant)
10/2021 - 01/2017
7Colorectal Neoplasms (Colorectal Cancer)
10/2018 - 01/2014
4Triple Negative Breast Neoplasms
11/2020 - 11/2019
2Adenocarcinoma
01/2021 - 01/2018
2Pancreatic Neoplasms (Pancreatic Cancer)
10/2020 - 01/2018
2Aneuploidy (Aneuploid)
11/2019 - 10/2018
1T-Cell Lymphoma (Lymphoma, T Cell)
01/2022
1Hematologic Neoplasms (Hematological Malignancy)
01/2021
1Adrenocortical Carcinoma
01/2020
1Polyploidy
01/2018
1Neoplasm Metastasis (Metastasis)
01/2018

Drug/Important Bio-Agent (IBA)

5Phosphotransferases (Kinase)IBA
10/2018 - 01/2014
4Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
10/2021 - 01/2014
4Immune Checkpoint InhibitorsIBA
01/2021 - 01/2020
3Proteins (Proteins, Gene)FDA Link
01/2018 - 01/2017
2Histones (Histone)IBA
01/2022 - 10/2019
2Biomarkers (Surrogate Marker)IBA
01/2022 - 10/2021
2Protein Isoforms (Isoforms)IBA
01/2022 - 01/2018
2adavosertibIBA
01/2021 - 03/2020
2Irinotecan (Camptosar)FDA LinkGeneric
01/2021 - 12/2017
2Capecitabine (Xeloda)FDA Link
01/2021 - 03/2020
2RX-5902IBA
11/2020 - 11/2019
2CateninsIBA
11/2020 - 11/2019
2Pharmaceutical PreparationsIBA
10/2020 - 01/2017
2Aurora Kinase AIBA
01/2020 - 01/2015
2MLN 8237IBA
01/2020 - 08/2016
2RNA (Ribonucleic Acid)IBA
01/2019 - 01/2018
1Histone Deacetylases (Histone Deacetylase)IBA
01/2022
1Histone Deacetylase InhibitorsIBA
01/2022
1palbociclibIBA
10/2021
1trametinibIBA
10/2021
1CytokinesIBA
01/2021
1GemcitabineFDA Link
10/2020
1Hormones (Hormone)IBA
03/2020
1sapanisertibIBA
01/2020
1Granzymes (Granzyme)IBA
01/2020
1Genetic Markers (Genetic Marker)IBA
01/2020
1pembrolizumabIBA
01/2020
1S63845IBA
01/2020
1navitoclaxIBA
01/2020
1Mechanistic Target of Rapamycin Complex 1IBA
01/2020
1UNC2025IBA
01/2019
1c-Mer Tyrosine KinaseIBA
01/2019
1VemurafenibIBA
01/2019
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2019
1ENMD 2076IBA
10/2018
1cabozantinibIBA
10/2018
1Chloroquine (Aralen)FDA LinkGeneric
10/2018
1tyrosine receptor (receptor, tyrosine)IBA
10/2018
1regorafenibIBA
10/2018
1SBI-0206965IBA
10/2018
1Immunoconjugates (Immunoconjugate)IBA
01/2018
1Enterotoxin ReceptorsIBA
01/2018
14- ((9- cyclopentyl- 7,7- difluoro- 5- methyl- 6- oxo- 6,7,8,9- tetrahydro- 5H- pyrimido(4,5- b)(1,4)diazepin- 2- yl)amino)- 2- fluoro- 5- methoxy- N- (1- methylpiperidin- 4- yl)benzamideIBA
01/2018
1Messenger RNA (mRNA)IBA
01/2018
1entrectinibIBA
01/2018
1AldosteroneIBA
01/2018
1Adenosine Triphosphate (ATP)IBA
01/2018
1indusatumabIBA
01/2018
1Enzyme Inhibitors (Inhibitors, Enzyme)IBA
01/2017
1pevonedistatIBA
01/2017
1TAK 733IBA
10/2015
1Drug CombinationsIBA
01/2015
1mirdametinibIBA
01/2014

Therapy/Procedure

10Therapeutics
10/2021 - 01/2015
3Immunotherapy
01/2021 - 01/2020
1Salvage Therapy
10/2021
1Drug Therapy (Chemotherapy)
01/2021
1Molecular Targeted Therapy
01/2020